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KMID : 0882419970520040570
Korean Journal of Medicine
1997 Volume.52 No. 4 p.570 ~ p.575
A Case of Pernicious Anemia with Positive Anti Intrinsic Factor Antibody and Antiparietal Cell Antibody


Park Young-Suk
Hahn Tai-Ho

Kang Seung-Sik

Lee Jung-Ae
Cho Sung-Tae


Jung Ji-Young
Park Chan-Jeong
Abstract
We present a case of pernicious anemia without history of operation in 52 year old female. She suffered from oral ulcer, gum bleeding, nausea, vomiting, and beefy tongue. She had dysesthesia on the both arm and foot, and hypesthesia of global and stocking type by neurologic examination. Laboratory findings were as follows: serum cobalamin 9.1 pg/mL (normal range: 180-710pg/mL), anti intrinsic factor antibody (strong positive), antiparietal cell Antibody 1:10 (positive), first stage of Schilling test (1.4%). The findings of peripheral blood and bone marrow were compatible with megaloblastic anemia. We report a case of pemicious anemia with positive anti intrinsic factor antibody and antiparietal cell antibody.
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