KMID : 0882419970520040570
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Korean Journal of Medicine 1997 Volume.52 No. 4 p.570 ~ p.575
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A Case of Pernicious Anemia with Positive Anti Intrinsic Factor Antibody and Antiparietal Cell Antibody
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Park Young-Suk Hahn Tai-Ho
Kang Seung-Sik
Lee Jung-Ae Cho Sung-Tae
Jung Ji-Young Park Chan-Jeong
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Abstract
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We present a case of pernicious anemia without history of operation in 52 year old female. She suffered from oral ulcer, gum bleeding, nausea, vomiting, and beefy tongue. She had dysesthesia on the both arm and foot, and hypesthesia of global and stocking type by neurologic examination. Laboratory findings were as follows: serum cobalamin 9.1 pg/mL (normal range: 180-710pg/mL), anti intrinsic factor antibody (strong positive), antiparietal cell Antibody 1:10 (positive), first stage of Schilling test (1.4%). The findings of peripheral blood and bone marrow were compatible with megaloblastic anemia. We report a case of pemicious anemia with positive anti intrinsic factor antibody and antiparietal cell antibody.
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KEYWORD
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